At the moment, There are 2 types of experiments on itaconate: Irg1−/− macrophages and also the regulatory outcome of itaconate derivatives. These two outcomes were being complementary and uncovered that the regulatory mechanisms of itaconate involved alkylation on Keap1 to activate Nrf2, succinate dehydrogenase inhibition, activating transcription component three (ATF3) https://felixvdpyb.mpeblog.com/53422586/the-single-best-strategy-to-use-for-recombinant-his