There is a release of norepinephrine with the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors within the dorsal horn to minimize afferent discomfort transmission and generate analgesia. Hence, medicine like clonidine that target alpha-2 receptors can influence the transmission of soreness. Critical Allergic Reactions. Clonidine might induce allergic https://geronimoh395ctl0.wikipowell.com/user